We at I2BF Global Ventures actively invest in Vertical SaaS startups that transform traditionally overlooked and underappreciated industries. Today, we’re excited to share an overview of 45 U.S. deals in this niche that closed in September 2025. You can also explore the list of Vertical SaaS startups that raised funding in January and February 2025, March 2025, April 2025, May 2025, June 2025, July 2025, and August 2025.
If you're building a Vertical SaaS business and planning to raise funding, feel free to reach out to us at info@i2bf.com. We’d be happy to discuss potential investment opportunities.
Series A+ Deals
Filevine raised a $260M Series E (total funding: $636M). The company provides operating intelligence for modern legal practices.
MarqVision raised a $48M Series B (total funding: $94.2M). The company offers an online brand protection solution, helping global brands identify and remove counterfeits from over 1,500 platforms and thousands of rogue websites.
Kojo raised a $10M Series C (total funding: $93.6M). It is the leading materials procurement platform for trade and self-performing general contractors.
Sight Machine raised an undisclosed venture round (total funding: $80M). It is a data platform for manufacturing, unlocking plant data to help manufacturers improve profitability, productivity, and sustainability.
EnTouch Controls raised a $50M venture round (total funding: $78M). The company provides SaaS-based energy management systems (EMS) for retail and restaurant chains.
Ketryx raised a $39M Series B (total funding: $57M). The company provides AI agents for FDA compliance.
Emerald AI raised an undisclosed venture round (total funding: $41.5M). The company provides a platform that enables AI data centers to flexibly adjust their power consumption from the electricity grid on demand.
Kodex raised a $21.2M venture round (total funding: $31.2M). The company offers a workflow management web platform that manages relationships, workflows, and secure file transfer with government agencies.
Turnkey Lender raised an undisclosed venture round (total funding: $23M). The company provides end-to-end loan management software.
Join raised an undisclosed venture round (total funding: $20M). The company offers a collaborative software platform for managing preconstruction and design phases of projects.
LightSpun raised a $13M Series A (total funding: $13M). It is an AI-powered platform designed to transform and streamline healthcare administration, specifically dental insurance.
Sleep.ai raised a $5.5M venture round (total funding: $12.3M). The company provides the world’s most advanced sleep intelligence platform.
RailPulse raised a $1M venture round (total funding: $11M). The platform provides real-time railcar data via GPS and other telemetry sensors installed on railcars across the North American fleet.
Simplifya raised a $2M venture round (total funding: $9.6M). It is a regulatory & operational compliance software for licensed cannabis businesses.
Vesta raised an undisclosed venture round (total funding: undisclosed). It is a next-generation loan origination system designed to modernize the aging mortgage technology infrastructure.
Ingest raised a $3.6M venture round (total funding: $7.4M). It is designed to streamline the property inspection process by providing real time accurate data, transparency and reduced costs.
Pre-Seed and Seed Rounds
Revalia Bio raised a $14.5M seed round (total funding: $19.5M). The company provides access to the Phase 0 human trial through a Platform-as-a-Service model that enables biomedical developers to design, track and interpret Phase 0 human trials.
Ankored raised a $4M seed round (total funding: $8.1M). Ankored is a software tool for anyone managing teams of coaches, volunteers, and staff, helping them execute all the required screenings, trainings, certifications and general paperwork without relying on spreadsheets, emails, or personal tenacity.
Nauta raised a $7M seed round (total funding: $7M). The company brings the power of AI to the global trade industry, connecting disparate data sources that operators rely on for the movement of every container.
Mazlo raised a $4.6M seed round (total funding: $5.7M). It is a FinTech company making it easier for fiscal sponsors and nonprofits practicing fiscal sponsorship to manage their finances and support their projects.
Landlord Tech raised a $3.5M seed round (total funding: $4.9M). It is a SaaS provider of property technology, focused to help property owners to manage their businesses.
Beagle Labs raised a $3.7M seed round (total funding: $4.3M). It is designed to streamline the property inspection process by providing real-time, accurate data, transparency, and reduced costs.
ChronicCareIQ raised a $2.5M seed round (total funding: $2.5M). The company provides software that helps clinics to care for chronic and complex patients.
FormlyAI raised a $2M seed round (total funding: $2M). It is a specialized AI-powered software platform that simplifies and streamlines medical device certification and compliance.
Wealthfeed raised a $2M seed round (total funding: $2M). The platform empowers financial advisors to grow their book of business and increase client retention using AI and big data.
LEA raised a $1.8M seed round (total funding: $1.9M). It is a SaaS company that offers an AI-powered workflow automation suite for wealth management services.
Landng raised a $20K pre-seed round (total funding: $515K). It is a SaaS MarTech company that drives sales of travel products through influencer marketing.
Data Operations raised an undisclosed pre-seed round (total funding: $225K). It is an AI-Powered Pricing & Competitor Intelligence platform that helps retailers and consumer brands win in competitive markets by combining dynamic pricing, promotion optimization, and real-time competitor insights.
ChargeBay raised an undisclosed seed round (total funding: $178K). The company provides an affordable, one-stop EV charging solution for multifamily and commercial properties throughout North America.
OpenDrawing raised a $20K pre-seed round (total funding: $20K). It is an AI tool that automates the creation of bills of materials from electrical single-line diagrams for engineers and estimators.
Circuitry.ai raised an undisclosed seed round (total funding: undisclosed). The company provides enterprise AI-as-a-Service applications for manufacturers to optimize sales and service outcomes using decision intelligence.
skyello raised an undisclosed seed round (total funding: undisclosed). It is an AI compliance enforcement platform for oil & gas, utilities, and industrial operators.
Y Combinator portfolio companies
Flai raised a $4.5M seed round (total funding: $5M). It is an AI-powered virtual assistant platform designed for enhancing dealership operations and customer engagement.
GroundControl raised a $2.5M seed round (total funding: $3M). The company provides software for first article inspections in manufacturing.
Parachute raised a $500K pre-seed round (total funding: $500K). The company provides governance infrastructure that helps hospitals evaluate, deploy, monitor, and audit clinical AI.
Lanesurf raised a $500K pre-seed round (total funding: $500K). The company offers an AI voice assistant to conduct and manage carrier calls, ensure compliance, and book freight loads programmatically.
Kalinda raised a $500K pre-seed round (total funding: $500K). The company automates the vetting of claimants using medical records according to specified criteria with AI.
Locata raised a $500K pre-seed round (total funding: $500K). The company provides an AI-powered referral management system for primary care providers.
Certus AI raised a $500K pre-seed round (total funding: $500K). The company utilizes voice automation to manage restaurant phone calls, including orders, reservations, complaints, payments, and POS system integration.
Palace raised a $500K pre-seed round (total funding: $500K). It is a unified platform for private market investment monitoring and reporting.
Serafis raised a $500K pre-seed round (total funding: $500K). It is an AI platform for investors and wealth advisors, designed to improve decision-making and product strategy.
Comena raised a $500K pre-seed round (total funding: $500K). It is an AI-powered platform that automates B2B order and inquiry processing for wholesalers and distributors.
Qualify.bot raised a $500K pre-seed round (total funding: $500K). It is an AI loan onboarding platform tailored for commercial loan brokers and lenders.
B-12 raised a $500K pre-seed round (total funding: $500K). It is an AI copilot for chemical lab experiments for pharma and biotech.
Perspectives Healthraised a $500K pre-seed round (total funding: $500K). It is an AI tool designed to streamline administrative tasks for behavioral health clinics.
